Marques Douglas grew up in Greensboro, North Carolina, where he played High School Football at James B. Dudley. He went on to play college football at Howard as both a  defensive tackle and defensive end – where he earned 3x All-Conference honors. After college, Howard signed with the Baltimore Ravens as an Undrafted Free Agent and ultimately played for five teams in the National Football League during an 11-year career. Douglas played for the Ravens, New Orleans Saints, San Francisco 49ers, New York Jets and the Tennessee Titans. He also played for Rhein Fire, an NFL Europe team, and was on the roster of the Miami Dolphins and Tampa Bay Buccaneers.

As a professional, he amassed 456 tackles, 20.5 sacks, 7 forced fumbles and 10 pass deflections. He was also named All-NFL Europe in 2010.